LEADER 00000nam 22003498a 4500
001 982012036517
003 UkLCURL
008 120907s2013 flu b 001 0 eng
020 9781466577435|q(hardcover)
035 (DNLM)101591786
035 (DLC)2012036517
040 DNLM/DLC|cDLC
049 |jCU|k982012036517|ll|m%
050 4 RC 268.4 D6
082 00 616.99/4061|223
245 00 DNA repair and cancer :|bfrom bench to clinic /|ceditors,
Srinivasan Madhusudan, David M. Wilson III.
260 Boca Raton, Fla. :|bTaylor & Francis,|c2013.
263 1312
300 700 p. ;|ccm.
505 0 Overview of DNA repair pathways / Deborah L. Croteau and
Vilhelm A. Bohr -- Longevity assurance by genome
maintenance / Paul Hasty, Yousin Suh and Jan Vijg --
Genetic instability of cancer : biological predictions and
clinical implications / Robert A. Beckman -- Radiation
induced DNA damage, repair, and therapeutics / Lynn
Harrison -- Chemotherapeutic alkylating agents in cancer
treatment / Tracey D. Bradshaw -- O6-methylguanine-DNA
methyltransferase (MGMT) in cancer protection and therapy
/ Bernd Kaina and Markus Christmann -- DNA mismatch repair
: it's role in human carcinogenesis and as a predictive
and/or prognostic biomarker for cancer therapy / Timothy
J. Kinsella -- DNA base excision repair therapeutics :
summary of targets with a focus on APE1 / Melissa L.
Fishel, Carlo Vascotto and Mark R. Kelley -- Nucleotide
excision repair : DNA repair capacity variability and
cancer susceptibility / Li-E Wang and Qingyi Wei --
Fanconi anemia, interstrand cross-link repair, and cancer
/ Taraswi Banerjee, Sanjay Kumar Bharti and Robert M.
Brosh, Jr -- Functions of translesion DNA polymerases :
implications for cancer risk and opportunities as
therapeutic targets / Kinrin Yamanaka and R. Stephen Lloyd
-- P53 in DNA damage, repair and cancer therapeutics /
Aditi Gurkar, Kiki Chu and Sam W. Lee -- ATM/ATR cell
cycle checkpoints : mechanisms and manipulation in cancer
therapy / Marie Fernet, Sara Chiker and Janet Hall -- The
BRCA1-BRCA2 pathway of homologous recombination and the
opportunity for synthetic lethal approaches to cancer
therapy / Laura J. Eccles ... [et al.] -- PARP and PARP
inhibitor therapeutics / Nicola J. Curtin -- Tumor
genetics and personalized medicine / Mary Ellen Urick and
Daphne W. Bell -- The tumor microenvironment and DNA
repair : implications for cancer progression and treatment
/ Norman Chan, Shaqil Kassam and Robert G. Bristow --
Early phase clinical trials using DNA repair inhibitors :
lessons learnt / Miranda Payne and Mark Middleton.
650 0 DNA repair.
650 0 Cancer|xChemotherapy.
700 1 Madhusudan, Srinivasan.
700 1 Wilson, David M.,|d1967-
