LEADER 00000nam 2200325 a 4500
001 0719436168
003 UkLCURL
008 120417s2013 enka 001 0 eng d
020 9781107601482|q(pbk.)
020 9781107013988|q(hardback)
035 (DNLM)101582503
035 (UkOxU)19436168
040 DNLM/DLC|cDLC|dUkOxU
049 |jCU|k0719436168|ll
050 4 RC 261 H5
082 00 616.99/4|223
100 1 Hesketh, Robin.
245 10 Introduction to cancer biology :|ba concise journey from
epidemiology through cell and molecular biology to
treatment and prospects /|cRobin Hesketh.
260 Cambridge :|bCambridge University Press,|c2013.
300 xvii, 335 p. :|bill. ;|c25 cm.
505 8 Machine generated contents note: Introduction; 1. Lessons
from epidemiology; 2. Causes of cancer; 3. Signalling in
normal cells; 4. 'Cancer genes': mutations and cancer
development; 5. What is a tumour?; 6. Cancer signalling
networks; 7. The future of cancer prevention, diagnosis
and treatment; 8. The future of cancer in the post-genomic
era; Ten major cancers at a glance; Appendix. Targets of
specific anti-cancer drugs; Glossary; Further reading;
Index.
520 "This concise overview of the fundamental concepts of
cancer biology is ideal for those with little or no
background in the field. A summary of global cancer
patterns introduces students to the general principles of
how cancers arise and the risk factors involved. By
focusing on fundamental examples of the signalling
pathways within cells, the functional effects of DNA
damage are explained. Later chapters then build on this
foundation to provide a comprehensive summary of the major
signalling pathways that affect tumour development.
Current therapeutic strategies are reviewed, along with a
discussion of methods for tumour detection and biomarker
identification. Finally, the impact of whole genome
sequencing is discussed, bringing students up to date with
key recent developments in the field. From basic
principles to insights into cutting-edge research, this
book will enable the reader to move into the cancer field
with confidence"--Provided by publisher.
650 0 Tumours.
650 0 Oncogenes.
650 0 Nucleotide sequence.
